HyperChem 8.0 Student Edition has every feature available in HyperChem 8.0 Professional, apart from a limitation on the number of atoms associated with energy computations. The same is expected in Student Edition 8. The atom limitations in molecular mechanics and quantum mechanics calculations are as follows:
| Ab Initio, DFT |
12 atoms |
| Semi-Empirical |
36 atoms |
| MM |
100 atoms |
| Amber, Charmm, OPLS |
1000 atoms |
Molecular systems of any size may be opened, drawn, manipulated and saved, but computations involving more than the above limits are not permitted.